Govardhan Reddy
Associate Professor
Solid State and Structural Chemistry Unit (SSCU),
Indian Institute of Science, Bangalore
Interests
- Biomolecular Simulations
- Polymer Physics
- Liquid State Theory
Education
-
PhD in Theoretical Chemistry, 2006
University of Wisconsin-Madison
-
BS/MS in Chemistry, 2001
Indian Institute of Technology, Bombay
Latest
- pH Regulates Ligand Binding to an Enzyme Active Site by Modulating Intermediate Populations
- pH Induced Switch in the Conformational Ensemble of Intrinsically Disordered Protein Prothymosin-α and Its Implications for Amyloid Fibril Formation
- Salt-Induced Transitions in the Conformational Ensembles of Intrinsically Disordered Proteins
- Local RNA Structure, Ion Hydration Shell and the Energy Barrier for Water Exchange from the Ion Hydration Shell Determine the Mechanism of Ion Condensation on Specific RNA Sites
- Mechanism of Mg2+ Mediated Encapsulation of an Anionic Cognate Ligand in a Bacterial Riboswitch
- TPP Riboswitch Populates Holo-Form-like Structure Even in the Absence of Cognate Ligand at High Mg2+ Concentration
- Energy Landscape of Ubiquitin is Weakly Multidimensional
- Asymmetry in Histone Rotation in Forced Unwrapping and Force Quench Rewrapping in a Nucleosome
- Double Domain Swapping in Human γC and γD Crystallin Drives Early Stages of Aggregation
- Mg2+ Sensing by an RNA Fragment: Role of Mg2+-Coordinated Water Molecules
- Mutual Diffusivity of an n‑Hexane-2,2-Dimethyl Butane Binary Mixture Confined to Zeolite Y
- Cosolvent Effects on the Growth of Amyloid Fibrils
- Shared Hydrogen Bonds: Water in Aluminated Faujasite
- Role of Guanidinium-Carboxylate Ion Interaction in Enzyme Inhibition with Implications for Drug Design
- A Transient Intermediate Populated in Prion Folding Leads to Domain Swapping
- Universal Nature of Collapsibility in the Context of Protein Folding and Evolution
- Transition State Ensemble in Salt Induced Protein Folding Follows Hammond's Postulate
- Role of Disulfide Bonds and Topological Frustration in the Kinetic Partitioning of Lysozyme Folding Pathways
- Cosolvent Effects on the Growth of Protein Aggregates Formed by a Single Domain Globular Protein and an Intrinsically Disordered Protein
- Contrasting Effects of Guanidinium Chloride and Urea on the Activity and Unfolding of Lysozyme
- Salt Effects on Protein Folding Thermodynamics
- Transient Intermediates are Populated in the Folding Pathways of Single-Domain Two-State Folding Protein L
- Thermodynamics and Kinetics of Single-Chain Monellin Folding with Structural Insights into Specific Collapse in the Denatured State Ensemble
- Toroidal Condensates by Semiflexible Polymer Chains: Insights into Nucleation, Growth and Packing Defects
- Suppression of the Coffee-Ring Effect and Evaporation-Driven Disorder to Order Transition in Colloidal Droplets
- Collapse Precedes Folding in Denaturant-Dependent Assembly of Ubiquitin
- Osmolyte Effects on the Growth of Amyloid Fibrils
- Folding of Protein L with Implications for Collapse in the Denatured State Ensemble
- Folding PDZ2 Domain Using the Molecular Transfer Model
- Dissecting Ubiquitin Folding Using the Self-Organized Polymer Model
- Structural Basis for the Catalytic Mechanism of Homoserine Dehydrogenase
- Propensity to Form Amyloid Fibrils Is Encoded as Excitations in the Free Energy Landscape of Monomeric Proteins
- Protein Folding: From Theory to Practice
- Denaturant-Dependent Folding of GFP
- Theory of the Molecular Transfer Model for Proteins with Applications to the Folding of the src-SH3 Domain
- Are Native Proteins Metastable?
- Entropic Stabilization of Proteins by TMAO
- Role of Water in Protein Aggregation and Amyloid Polymorphism
- Collapse Kinetics and Chevron Plots from Simulations of Denaturant-Dependent Folding of Globular Proteins
- Dry Amyloid Fibril Assembly in a Yeast Prion Peptide is Mediated by Long-Lived Structures Containing Water Wires
- Factors Governing Fibrillogenesis of Polypeptide Chains Revealed by Lattice Models
- Solvent Effects in Polyelectrolyte Adsorption: Computer Simulations with Explicit and Implicit Solvent
- Dynamics of Locking of Peptides onto Growing Amyloid Fibrils
- Water-Mediated Interactions Between Hydrophobic and Ionic Species in Cylindrical Nanopores
- Influence of Preformed Asp23−Lys28 Salt Bridge on the Conformational Fluctuations of Monomers and Dimers of Aβ Peptides with Implications for Rates of Fibril Formation
- Protein Folding, Misfolding and Aggregation: Classical Themes and Novel Approaches
- Implicit and Explicit Solvent Models for the Simulation of Dilute Polymer Solutions
- Adsorption and Dynamics of a Single Polyelectrolyte Chain near a Planar Charged Surface: Molecular Dynamics Simulations with Explicit Solvent
- Integral Equation Theory for Symmetric Nonadditive Hard Sphere Mixtures
- The Behavior of Fluids Near Solutes: A Density Functional Theory and Computer Simulation Study
- Liquid State Theories for the Structure of Water